General Manager

Job Title: General Manager

Location: India – remote Position

Why Join us Now

Radiopharmaceutical are redefining cancer treatment and actinium pharmaceuticals (NYSE:ATNM) is at the forefront. We are building first-in-class targeted radiotherapies by combining deep radiochemistry expertise with cancer biology insight, creating platform-level opportunities across solid tumors and hematologic malignancies.

The Opportunity

The General Manager will build and lead Actinium’s India platform at a pivotal moment in radiopharmaceutical innovation. This role owns the end-to-end strategy and execution across manufacturing, clinical development, and regulatory engagement transforming India into a core drive of Actinium’s global oncology pipeline. This is a hands-on, high impact leadership role for someone excited to build, influence, and deliver shaping how Actinium advances targeted alpha therapies from clinical promise to real-world impact.

Your Impact

Country Strategy & Platform Build

• Own and execute Actinium’s India strategy for oncology clinical development and radiopharmaceutical manufacturing, aligned with global objectives
• Establish the Actinium India Innovation Center and build the company’s presence in a leading biotech hub
• Serve as a senior strategic partner to U.S. and EU leadership, translating global priorities into local execution

Manufacturing, Supply Chain & CMC Leadership

• Stand up and scale local GMP drug product manufacturing to support clinical and early commercial supply
• Provide senior oversight of radiopharmaceutical manufacturing operations, including facility design, qualification, validation, and inspection readiness
• Lead tech transfer from global development teams into India-based manufacturing
• Ensure tight integration across manufacturing, QA/QC, supply chain, and clinical operations
• Drive manufacturing governance (deviations, CAPAs, change control, batch release, audits) in line with Actinium global standards
• Optimize radiopharmaceutical logistics and distribution in compliance with Indian and international regulations

Clinical Development & Hospital Alliances

• Enable high-quality, cost-efficient, signal-seeking oncology trials across major solid tumors
• Oversee all country-level clinical operations, including feasibility, site selection, activation, contracts, budgets, CRO oversight, and monitoring
• Build and deepen strategic hospital partnerships with leading oncologists, KOLs, and research institutions
• Serve as the primary executive point of contact for clinical and regulatory matters within hospital alliances
• Identify and champion opportunities to expand and enhance alliance value

Regulatory Strategy & Compliance

• Lead or partner to build local regulatory capabilities and streamline interactions with CDSCO / DCGI / CTRI
• Ensure compliance with Indian regulations, GCP, and ICH guidelines
• Support clinical trial approvals, import licenses, and manufacturing licenses
• Lead responses to regulatory inspections and audits, ensuring timely and accurate submissions
• Enable generation of globally relevant clinical and CMC data from India

Operational, Financial & Organizational Leadership

• Establish and operate the India legal entity, including registrations and statutory filings
• Own site P&L and budget, driving efficiency without compromising quality or compliance
• Ensure compliance with Indian labor law and Actinium policies
• Act as the cross-site connector between India teams and U.S./EU functions, enabling knowledge transfer and joint planning

Risk Management & Execution Excellence

• Proactively identify and mitigate clinical, regulatory, manufacturing, and operational risks
• Lead cross-functional problem-solving on complex, high-impact issues
• Escalate critical risks and decisions to senior leadership with clarity and speed

What you Need

• Advanced degree (Bachelor’s or Master’s) in a scientific or health-related discipline (e.g., Biology, Pharmacy, Pharmaceutical Chemistry)
• Senior leadership experience in biotech, clinical development, manufacturing, or regulatory affairs ideally within oncology or radiopharmaceuticals
• Proven track record leading oncology clinical trials, including budgeting, resourcing, and execution
• Deep understanding of Indian clinical and regulatory requirements (CDSCO / DCGI / CTRI) and global standards (GCP, ICH)
• Experience managing strategic partnerships and hospital alliances
• Strong ability to operate in a cross-functional, matrixed global environment
• Exceptional analytical, problem-solving, communication, and negotiation skills
• Comfortable owning outcomes, managing complexity, and executing under pressure
• High cultural fluency: English required, additional local languages a plus

Actinium is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat all employees and applicants on the basis of merit, qualifications, and competence. The company’s policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of protected Veterans status, individuals with disabilities status, and consistent with all federal, state or local laws.

Advanced scientific or health-related degree, senior biotech leadership, oncology trial leadership, Indian regulatory expertise, strategic partnership experience, and strong analytical, communication, and negotiation skills.

Key Responsibilities

• leading strategy
• overseeing manufacturing
• managing alliances

Skills & Tools

GCP, ICH, CDSCO, DCGI, CTRI, CAPA

Job Details

• Category: Business Operations
• Seniority: Senior Level
• Commitment: Full Time
• Workplace: Remote — India
• Languages: English

About Actinium Pharmaceuticals, Inc.

A biopharmaceutical company developing targeted alpha therapies for cancer treatment. — Industry: Healthcare