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[Remote] Senior Full-Stack Engineer

Work from home Full-time role Hiring

Note: The job is a remote job and is open to candidates in USA. Plenful is a healthcare AI workflow automation company helping pharmacy and health system teams reduce manual work and improve compliance. The Senior Full-Stack Engineer will build and own customer-facing features end to end across workflows such as 340B compliance, intake, rebate management, and claims reconciliation, while contributing to the platform’s technical foundation and AI capabilities.

Responsibilities

  • Build and ship full-stack features end to end, from the database to the UI, for workflows like 340B compliance, intake, rebate management, and claims reconciliation
  • Partner directly with product managers and pharmacy operations experts to understand what pharmacy teams actually need, not just what's in the ticket
  • Own what you ship: design it, build it, test it, deploy it, and support it in production
  • Make sound tradeoffs between speed and durability as Plenful scales its platform to serve more health systems
  • Contribute to the technical foundation of the platform, including how AI gets embedded into product workflows
  • Use AI tools deliberately as part of how you work, not just how you demo
  • Review code, weigh in on design docs, and help raise the technical bar across the team

Skills

  • You've spent 7+ years in professional software engineering, working across the stack
  • You're proficient in JavaScript and TypeScript, with working proficiency in Python
  • You've built customer-facing products — not primarily internal tooling or developer platforms
  • You're comfortable moving across layers of the stack instead of staying in one
  • You've worked in a fast-moving, high-growth environment where priorities shift as the product and customer base scale
  • You have strong instincts for what "production-ready" means in a compliance-critical, enterprise healthcare context
  • You communicate clearly with product, design, and non-technical stakeholders
  • You're open to being based in San Francisco (hybrid, in-office Mondays and Wednesdays) or Chicago (remote)
  • Bonus points for experience with Java or Ruby (if you don't know Python, you're willing to learn it), healthcare or pharmacy experience, or a track record at startups that scaled from 0 to 1 and beyond

Benefits

  • Strengthen your expertise through collaboration with experienced, high-performing leaders across the organization
  • Flexible Hybrid Work Environment — We're remote-first, with meaningful office presence in San Francisco and New York. R&D roles follow a hybrid model, with two days per week in our San Francisco office
  • Healthcare Coverage — Full medical, dental, and vision insurance for you and participation for your family
  • 401(k) with Company Match — Plenful matches 50% of your first 3% contributed
  • Equity — Every full-time employee shares in our success
  • Unlimited PTO — Take the time you need, when you need it
  • Daily Lunch Stipend — $100/week to cover your midday meals
  • Wellness Stipend — $100/month to support your health and well-being
  • Commuter Benefits — $100/month for SF and NYC-based employees
  • Parental Leave — Paid leave to support growing families

Company Overview

  • Plenful is a no-code workflow automation and AI platform that optimizes healthcare's manual, administrative workflows. It was founded in 2021, and is headquartered in San Francisco, California, USA, with a workforce of 51-200 employees. Its website is https://www.plenful.com.
  • Company H1B Sponsorship

  • Plenful has a track record of offering H1B sponsorships, with 1 in 2026, 3 in 2025, 1 in 2023, 1 in 2022. Please note that this does not guarantee sponsorship for this specific role.
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