← all jobs

[Remote] Sr. AI-First Full Stack Engineer

Work from home Full-time role Hiring

Note: The job is a remote job and is open to candidates in USA. McKesson is an impact-driven healthcare company seeking a Senior AI-First Full Stack Engineer to build intelligent technology solutions for specialty pharmacy and healthcare operations. The role involves developing full stack and Generative AI applications, designing integrations and cloud-native architectures, and owning solutions throughout the software lifecycle from discovery through production support.

Responsibilities

  • Design, develop, and deploy AI-powered applications using Claude (Anthropic), Azure OpenAI, OpenAI, and Azure AI Services
  • Partner directly with business stakeholders to define problems, validate workflows, rapidly prototype solutions, and convert successful concepts into production capabilities
  • Build RAG solutions, prompt frameworks, AI workflows, and autonomous or agentic systems with human-in-the-loop controls
  • Develop full stack applications using React, TypeScript, Python, C#, Java, Node.js, and .NET
  • Design REST APIs, microservices, event-driven architectures, and enterprise integration patterns
  • Integrate AI capabilities with ServiceNow, Salesforce, Snowflake, Databricks, Power BI, and other enterprise platforms
  • Develop cloud-native solutions on Microsoft Azure using secure engineering and DevOps practices
  • Build CI/CD pipelines, Infrastructure as Code, containerized workloads, and Kubernetes deployments
  • Serve as technical owner for assigned applications or platforms, establishing architecture standards, engineering guardrails, SLOs, and production-readiness criteria
  • Lead modernization, technical debt reduction, resiliency improvements, design reviews, incident resolution, and root-cause prevention
  • Mentor engineers and influence architecture, security, data, product, and delivery decisions across teams

Skills

  • 7+ years of professional software engineering experience developing enterprise-scale applications
  • Bachelor's degree in Computer Science, Engineering, Information Technology, or a related field, or equivalent practical experience
  • Hands-on experience building and deploying applications using Java, Node.js, C#, Python, or comparable backend technologies
  • Experience developing modern front-end applications using React and TypeScript
  • Experience designing and consuming REST APIs, microservices, and enterprise integrations
  • Experience developing cloud-native applications on Microsoft Azure
  • Experience with CI/CD, source control, automated testing, SDLC, and Agile practices
  • Experience acting as a technical lead or primary owner for an enterprise application, service, or platform
  • Experience designing scalable architectures, documenting trade-offs, and supporting production systems
  • Demonstrated ability to turn ambiguous business needs into delivered technical solutions
  • Ability to work on a computer for extended periods and participate in virtual collaboration activities
  • Experience with Azure AI Services, Azure OpenAI, Azure AI Foundry, Cognitive Services, and enterprise AI platforms
  • Experience building Generative AI solutions using Azure OpenAI, OpenAI, Claude, or comparable LLM platforms
  • Strong programming experience with Python, C#, TypeScript, JavaScript, Java, and .NET technologies
  • Experience developing full stack applications using React, TypeScript, Node.js, Python, and C#/.NET
  • Experience designing, developing, securing, and supporting REST APIs and enterprise integration services
  • Experience with Databricks, Snowflake, and governed enterprise data and analytics platforms
  • Experience with RAG, semantic search, vector databases, AI orchestration, agentic AI, guardrails, evaluation, and human-in-the-loop workflows
  • Experience with Salesforce platform development, integrations, REST APIs, workflows, and data services
  • Experience integrating with or supporting ServiceNow workflows, ITSM, CMDB, service catalog, and automation processes
  • Experience developing data visualization, analytics, and operational reporting solutions using Power BI
  • Experience with Docker, Kubernetes, Infrastructure as Code, Azure Monitor, Application Insights, or comparable platforms
  • Knowledge of distributed systems, event-driven architecture, asynchronous processing, and resiliency patterns
  • Experience leading application modernization, cloud transformation, or platform engineering initiatives
  • Experience in healthcare, specialty pharmacy, regulated industries, or high-compliance environments
  • Limited travel may be required for collaboration, planning, stakeholder discovery, or solution workshops

Benefits

  • Hybrid or remote work arrangement based on business needs.
  • An annual bonus may be offered.
  • Long-term incentive opportunities may be offered.

Company Overview

  • McKesson distributes medical supplies, information technology, and care management products and services. It was founded in 1833, and is headquartered in Irving, Texas, USA, with a workforce of 10001+ employees. Its website is http://www.mckesson.com.
  • Company H1B Sponsorship

  • McKesson has a track record of offering H1B sponsorships, with 40 in 2026, 149 in 2025, 129 in 2024, 82 in 2023, 142 in 2022, 144 in 2021, 154 in 2020. Please note that this does not guarantee sponsorship for this specific role.
  • More open positions

    [Remote] Account Manager

    Work from home Full-time role

    [Remote] Sales Professional - Eastern NC & Southeast VA

    Work from home Full-time role

    [Remote] Manager, Provider Network Operations

    Work from home Full-time role

    [Remote] Consulting Actuary (ASA) - Medicaid (CMH Health)

    Work from home Full-time role

    [Remote] Senior Full Stack Software Development Engineer

    Work from home Full-time role

    Remote Physician

    Work from home Full-time role

    PCT Patent Analyst (Contract) - Mechanical/Medical Devices

    Work from home Full-time role

    [Remote] Engineer, Mechanical or Electrical (Construction Project Development)

    Work from home Full-time role

    Respite Crisis Services Support Specialist

    Work from home Full-time role

    [Remote] Full Stack Engineer

    Work from home Full-time role

    Home Health PTA

    Work from home Full-time role

    Contracts and Privacy Manager

    Work from home Full-time role

    Engineering Lead

    Work from home Full-time role

    Regional HRBP

    Work from home Full-time role

    Remote AR & Patient Collections Specialist – Mental Health

    Work from home Full-time role

    Sr Sales Account Manager

    Work from home Full-time role

    Seasoned Remote Customer Service Representative – Global Travel Support Specialist for talentflow

    Work from home Full-time role

    Proposal Manager Energy

    Work from home Full-time role

    Mega Projects Enterprise Estimator -Water/Wastewater Treatment Plant - CIG

    Work from home Full-time role

    Safety Science Specialist

    Work from home Full-time role

    Junior Contracts Analyst (Remote)

    Work from home Full-time role