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[Remote] Sr. Technical Program Manager, AI Security

Remote Full-time Now Hiring

Note: The job is a remote job and is open to candidates in USA. Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of AI-readiness initiatives at Moderna globally. The role involves managing complex workstreams, ensuring effective collaboration, and advancing infrastructure and security practices within AI systems.

Responsibilities

  • Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting
  • Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process
  • Build processes, templates, and structure, or leverage existing ones as appropriate
  • Manage vendors, schedule, scope, and cost
  • Measure program success (or lack thereof) and risks using data and facts
  • Provide balanced risk remediation strategies and recommendations and drive risk mitigation
  • Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna
  • Provide clear, accurate, consistent, and timely communications
  • Advance good infrastructure and security practices and culture
  • Partner Collaboration - work with Cybersecurity, Builder Tools & Platforms, Infrastructure, Identity & Endpoint Engineering, GRC, AI Engineering, Data, Enablement/L&D, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner
  • Manage multiple initiatives to oversee the architecture and lifecycle of enterprise AI systems, including agent identity, tool authorization, and secure development practices; to drive governance frameworks that define permitted AI use, contextual standards, and regulatory alignment — including GxP where applicable; and to ensure end-to-end observability and monitoring of AI agents in production
  • Own the operating model for AI enablement programs, including pilots, cohorts, and phased rollouts, and partner with Enablement/L&D teams to shape role‑based learning paths for AI builders
  • Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain antiracist policies and processes

Skills

  • 8+ years of Technical Program Management or Engineering Program Management in Artificial Intelligence (AI) / Machine Learning (ML) heavy environments is required
  • Background in software engineering, data science, or machine learning
  • Experience with LLM platforms, prompt engineering workflows, or AI copilots
  • Experience with AI development platforms, copilots, developer tooling, or MLOps concepts
  • Experience with responsible AI, model governance, or compliance frameworks
  • Experience driving structured, process-driven AI transformation initiatives
  • Familiarity with tools such as Kubernetes, Airflow, MLFlow, or similar MLOps stacks
  • Familiarity with governed enablement models (e.g., citizen development, platform standards, golden paths)
  • Knowledge of security and compliance standards relevant to AI and AI-assisted engineering
  • Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders
  • Embrace a culture of continuous service improvement and service excellence
  • A desire to make an impact as part of a high-growth, transformational company
  • Experience with GxP environments and regulatory requirements
  • Technical Depth: Strong understanding of AI/ML systems, including model training pipelines, LLMs, MLOps, data pipelines, and cloud infrastructure
  • Strong understanding of AI/ML development workflows, AI-assisted engineering tools, or modern software development platforms
  • Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills
  • Experience in running programs within a cross-functional, global team of mixed engineering, architecture, and operations
  • Ability to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion
  • Experience improving developer productivity and building internal tools/platforms
  • Ability to define metrics, analyze tradeoffs, and drive decisions with data
  • Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback
  • Proven ability to operate in highly matrixed environments and influence without direct authority
  • Excellent written and verbal communication skills, including executive-level storytelling

Benefits

  • Competitive healthcare, plus voluntary benefit programs to support your unique needs
  • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
  • Family planning benefits, including fertility, adoption, and surrogacy support
  • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
  • Savings and investments to help you plan for the future
  • Location-specific perks and extras
  • The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance

Company Overview

  • Moderna Therapeutics is a biotechnology company that develops medicines and vaccines based on messenger RNA (mRNA) technology. It was founded in 2010, and is headquartered in Cambridge, Massachusetts, USA, with a workforce of 1001-5000 employees. Its website is http://www.modernatx.com.